Evolutionary and reverse engineering in Saccharomyces cerevisiae reveals a Pdr1p mutation-dependent mechanism for 2-phenylethanol tolerance

BACKGROUND: 2-Phenylethanol (2-PE), a higher alcohol with a rose-like odor, inhibits growth of the producer strains. However, the limited knowledge regarding 2-PE tolerance mechanisms renders our current knowledge base insufficient to inform rational design. RESULTS: To improve the growth phenotype...

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Detalles Bibliográficos
Autores principales: Xia, Huili, Kang, Yue, Ma, Zilin, Hu, Cuiyu, Yang, Qiao, Zhang, Xiaoling, Yang, Shihui, Dai, Jun, Chen, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789650/
https://www.ncbi.nlm.nih.gov/pubmed/36564756
http://dx.doi.org/10.1186/s12934-022-01996-x

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