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Cross-sectional study to assess awareness of cytomegalovirus infection among pregnant women in Germany

BACKGROUND: Study aimed to assess awareness of congenital cytomegalovirus (CMV) infection and its determinants in pregnancy. METHODS: Cross-sectional survey was conducted in five hospital-based maternity units in Germany. Pregnant women attending the maternity departments completed interviewer/self-...

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Autores principales: Greye, Hannah, Henning, Stine, Freese, Kristina, Köhn, Andrea, Lux, Anke, Radusch, Anja, Redlich, Anke, Schleef, Daniela, Seeger, Sven, Thäle, Volker, Rissmann, Anke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789651/
https://www.ncbi.nlm.nih.gov/pubmed/36566184
http://dx.doi.org/10.1186/s12884-022-05312-8
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author Greye, Hannah
Henning, Stine
Freese, Kristina
Köhn, Andrea
Lux, Anke
Radusch, Anja
Redlich, Anke
Schleef, Daniela
Seeger, Sven
Thäle, Volker
Rissmann, Anke
author_facet Greye, Hannah
Henning, Stine
Freese, Kristina
Köhn, Andrea
Lux, Anke
Radusch, Anja
Redlich, Anke
Schleef, Daniela
Seeger, Sven
Thäle, Volker
Rissmann, Anke
author_sort Greye, Hannah
collection PubMed
description BACKGROUND: Study aimed to assess awareness of congenital cytomegalovirus (CMV) infection and its determinants in pregnancy. METHODS: Cross-sectional survey was conducted in five hospital-based maternity units in Germany. Pregnant women attending the maternity departments completed interviewer/self-administered survey questionnaire. High-risk group was defined according to contact with children under five years of age (at home or at work). Quantitative analyses using multivariable logistic regression were performed. RESULTS: One thousand two hundred thirty-three pregnant women were included. 48.5% (n = 598) of women reported any knowledge about risk of CMV infection during pregnancy. CMV infection was less known than other infections or diseases (education about toxoplasmosis 95.5% (n = 1,177), listeriosis 60.5% (n = 746). 38% (n = 468) of participants received education about CMV. CMV awareness was associated with the level of education and employment in childcare or medical care. Only 32% (n = 394) of the women made use of serological screening for CMV during pregnancy (individual health service). 40.8% (n = 503) of pregnant women were classified as high-risk group. They had significantly higher knowledge and education about CMV, and msignificantlycant more often use of the serological screening. CONCLUSIONS: Less than half of pregnant women surveyed were aware of potential risk associated with CMV infection during pregnancy. In our study,one-third third of pregnant women made use of the serological screening for CMV. Regarding the lack of current consensus on the role of serological CMV screening for pregnant women, hygiene preventive measures are the only evidence-based recommendation for pregnant women and knowledge increase could potentially have major public health impact. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-022-05312-8.
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spelling pubmed-97896512022-12-25 Cross-sectional study to assess awareness of cytomegalovirus infection among pregnant women in Germany Greye, Hannah Henning, Stine Freese, Kristina Köhn, Andrea Lux, Anke Radusch, Anja Redlich, Anke Schleef, Daniela Seeger, Sven Thäle, Volker Rissmann, Anke BMC Pregnancy Childbirth Research BACKGROUND: Study aimed to assess awareness of congenital cytomegalovirus (CMV) infection and its determinants in pregnancy. METHODS: Cross-sectional survey was conducted in five hospital-based maternity units in Germany. Pregnant women attending the maternity departments completed interviewer/self-administered survey questionnaire. High-risk group was defined according to contact with children under five years of age (at home or at work). Quantitative analyses using multivariable logistic regression were performed. RESULTS: One thousand two hundred thirty-three pregnant women were included. 48.5% (n = 598) of women reported any knowledge about risk of CMV infection during pregnancy. CMV infection was less known than other infections or diseases (education about toxoplasmosis 95.5% (n = 1,177), listeriosis 60.5% (n = 746). 38% (n = 468) of participants received education about CMV. CMV awareness was associated with the level of education and employment in childcare or medical care. Only 32% (n = 394) of the women made use of serological screening for CMV during pregnancy (individual health service). 40.8% (n = 503) of pregnant women were classified as high-risk group. They had significantly higher knowledge and education about CMV, and msignificantlycant more often use of the serological screening. CONCLUSIONS: Less than half of pregnant women surveyed were aware of potential risk associated with CMV infection during pregnancy. In our study,one-third third of pregnant women made use of the serological screening for CMV. Regarding the lack of current consensus on the role of serological CMV screening for pregnant women, hygiene preventive measures are the only evidence-based recommendation for pregnant women and knowledge increase could potentially have major public health impact. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12884-022-05312-8. BioMed Central 2022-12-24 /pmc/articles/PMC9789651/ /pubmed/36566184 http://dx.doi.org/10.1186/s12884-022-05312-8 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Greye, Hannah
Henning, Stine
Freese, Kristina
Köhn, Andrea
Lux, Anke
Radusch, Anja
Redlich, Anke
Schleef, Daniela
Seeger, Sven
Thäle, Volker
Rissmann, Anke
Cross-sectional study to assess awareness of cytomegalovirus infection among pregnant women in Germany
title Cross-sectional study to assess awareness of cytomegalovirus infection among pregnant women in Germany
title_full Cross-sectional study to assess awareness of cytomegalovirus infection among pregnant women in Germany
title_fullStr Cross-sectional study to assess awareness of cytomegalovirus infection among pregnant women in Germany
title_full_unstemmed Cross-sectional study to assess awareness of cytomegalovirus infection among pregnant women in Germany
title_short Cross-sectional study to assess awareness of cytomegalovirus infection among pregnant women in Germany
title_sort cross-sectional study to assess awareness of cytomegalovirus infection among pregnant women in germany
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789651/
https://www.ncbi.nlm.nih.gov/pubmed/36566184
http://dx.doi.org/10.1186/s12884-022-05312-8
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