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Cyclin G2 in macrophages triggers CTL-mediated antitumor immunity and antiangiogenesis via interferon-gamma

BACKGROUND: IFN-γ is a key mediator of tumor immunity that can induce macrophage polarization to suppress tumor growth. Cyclin G2 functions as a tumor suppressor in various cancer cells; however, its role in macrophages remains unclear. This study aimed to investigate the role and underlying mechani...

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Detalles Bibliográficos
Autores principales: Liu, Lu, Gao, Jinlan, Xing, Xuesha, Jiang, Meixi, Liu, Qi, Wang, Shusen, Luo, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789679/
https://www.ncbi.nlm.nih.gov/pubmed/36566226
http://dx.doi.org/10.1186/s13046-022-02564-2

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