Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic

Parkinsonism refers to the clinical combination of bradykinesia, rigidity, tremor, and postural instability. Parkinsonism is often neurodegenerative, but it can be secondary or iatrogenic, as in drug-induced parkinsonism (DIP), which is the topic of this review. We review the pathophysiology of DIP,...

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Detalles Bibliográficos
Autores principales: Feldman, Matthew, Marmol, Sarah, Margolesky, Jason
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789682/
https://www.ncbi.nlm.nih.gov/pubmed/36573102
http://dx.doi.org/10.2147/TCRM.S360268
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author Feldman, Matthew
Marmol, Sarah
Margolesky, Jason
author_facet Feldman, Matthew
Marmol, Sarah
Margolesky, Jason
author_sort Feldman, Matthew
collection PubMed
description Parkinsonism refers to the clinical combination of bradykinesia, rigidity, tremor, and postural instability. Parkinsonism is often neurodegenerative, but it can be secondary or iatrogenic, as in drug-induced parkinsonism (DIP), which is the topic of this review. We review the pathophysiology of DIP, differentiate DIP and idiopathic Parkinson’s disease (PD), list culprit medications in the development of DIP, discuss the diagnosis of DIP as well as the motor and nonmotor signs and symptoms that can help with differentiation of DIP and PD, and detail the management of DIP.
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spelling pubmed-97896822022-12-25 Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic Feldman, Matthew Marmol, Sarah Margolesky, Jason Ther Clin Risk Manag Review Parkinsonism refers to the clinical combination of bradykinesia, rigidity, tremor, and postural instability. Parkinsonism is often neurodegenerative, but it can be secondary or iatrogenic, as in drug-induced parkinsonism (DIP), which is the topic of this review. We review the pathophysiology of DIP, differentiate DIP and idiopathic Parkinson’s disease (PD), list culprit medications in the development of DIP, discuss the diagnosis of DIP as well as the motor and nonmotor signs and symptoms that can help with differentiation of DIP and PD, and detail the management of DIP. Dove 2022-12-20 /pmc/articles/PMC9789682/ /pubmed/36573102 http://dx.doi.org/10.2147/TCRM.S360268 Text en © 2022 Feldman et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Feldman, Matthew
Marmol, Sarah
Margolesky, Jason
Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic
title Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic
title_full Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic
title_fullStr Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic
title_full_unstemmed Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic
title_short Updated Perspectives on the Management of Drug-Induced Parkinsonism (DIP): Insights from the Clinic
title_sort updated perspectives on the management of drug-induced parkinsonism (dip): insights from the clinic
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789682/
https://www.ncbi.nlm.nih.gov/pubmed/36573102
http://dx.doi.org/10.2147/TCRM.S360268
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