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Eosinophilic pulmonary granulomatosis resembling a pulmonary carcinoma in a dog in Hong Kong
BACKGROUND: Canine Eosinophilic Pulmonary Granulomatosis (EPG) is a severe form of eosinophilic pulmonary disease that carries a guarded prognosis, responds poorly to therapy and recurs frequently. Most studies have reported a caudal lobar pulmonary distribution and a poorer prognosis in idiopathic...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculty of Veterinary Medicine
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789769/ https://www.ncbi.nlm.nih.gov/pubmed/36589391 http://dx.doi.org/10.5455/OVJ.2022.v12.i5.3 |
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author | Almendros, Angel Lai, Sin Yi Giuliano, Antonio |
author_facet | Almendros, Angel Lai, Sin Yi Giuliano, Antonio |
author_sort | Almendros, Angel |
collection | PubMed |
description | BACKGROUND: Canine Eosinophilic Pulmonary Granulomatosis (EPG) is a severe form of eosinophilic pulmonary disease that carries a guarded prognosis, responds poorly to therapy and recurs frequently. Most studies have reported a caudal lobar pulmonary distribution and a poorer prognosis in idiopathic cases. CASE DESCRIPTION: A 7-year-old dog was presented for persistent cough, hyporexia, and weight loss. Eosinophilia and basophilia were transiently present, and an antigen test for heartworm disease was negative. Radiographic studies, followed by a computed tomography (CT) scan revealed nodular lesions and a large mass in the left cranial lobar region suggestive of neoplasia. Cytological and histopathological evaluation was consistent with EPG. The dog responded positively to corticosteroids and has since remained free of disease. CONCLUSION: EPG in dogs can resemble primary pulmonary neoplasia with secondary intra-pulmonary metastasis. Contrary to previous reports, idiopathic EPG can present with a cranial pulmonary distribution and respond positively to therapy. |
format | Online Article Text |
id | pubmed-9789769 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Faculty of Veterinary Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-97897692022-12-30 Eosinophilic pulmonary granulomatosis resembling a pulmonary carcinoma in a dog in Hong Kong Almendros, Angel Lai, Sin Yi Giuliano, Antonio Open Vet J Case Report BACKGROUND: Canine Eosinophilic Pulmonary Granulomatosis (EPG) is a severe form of eosinophilic pulmonary disease that carries a guarded prognosis, responds poorly to therapy and recurs frequently. Most studies have reported a caudal lobar pulmonary distribution and a poorer prognosis in idiopathic cases. CASE DESCRIPTION: A 7-year-old dog was presented for persistent cough, hyporexia, and weight loss. Eosinophilia and basophilia were transiently present, and an antigen test for heartworm disease was negative. Radiographic studies, followed by a computed tomography (CT) scan revealed nodular lesions and a large mass in the left cranial lobar region suggestive of neoplasia. Cytological and histopathological evaluation was consistent with EPG. The dog responded positively to corticosteroids and has since remained free of disease. CONCLUSION: EPG in dogs can resemble primary pulmonary neoplasia with secondary intra-pulmonary metastasis. Contrary to previous reports, idiopathic EPG can present with a cranial pulmonary distribution and respond positively to therapy. Faculty of Veterinary Medicine 2022 2022-09-05 /pmc/articles/PMC9789769/ /pubmed/36589391 http://dx.doi.org/10.5455/OVJ.2022.v12.i5.3 Text en https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Almendros, Angel Lai, Sin Yi Giuliano, Antonio Eosinophilic pulmonary granulomatosis resembling a pulmonary carcinoma in a dog in Hong Kong |
title | Eosinophilic pulmonary granulomatosis resembling a pulmonary carcinoma in a dog in Hong Kong |
title_full | Eosinophilic pulmonary granulomatosis resembling a pulmonary carcinoma in a dog in Hong Kong |
title_fullStr | Eosinophilic pulmonary granulomatosis resembling a pulmonary carcinoma in a dog in Hong Kong |
title_full_unstemmed | Eosinophilic pulmonary granulomatosis resembling a pulmonary carcinoma in a dog in Hong Kong |
title_short | Eosinophilic pulmonary granulomatosis resembling a pulmonary carcinoma in a dog in Hong Kong |
title_sort | eosinophilic pulmonary granulomatosis resembling a pulmonary carcinoma in a dog in hong kong |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789769/ https://www.ncbi.nlm.nih.gov/pubmed/36589391 http://dx.doi.org/10.5455/OVJ.2022.v12.i5.3 |
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