Distinct pattern and prevalence of Plasmodium falciparum dihydropteroate synthase gene mutations in children with sickle cell anaemia and haemoglobin AA in Benin City, Nigeria: the impact of HbAA

INTRODUCTION: specific mutations on the Plasmodium falciparum dihydropteroate synthase (Pfdhps) gene mediate sulphadoxine/pyrimethamine (SP) resistance and thus, pose a threat to the efficacy of SP-Intermittent Preventive Therapy (SP-IPT) in malaria chemoprevention in children, including those with...

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Detalles Bibliográficos
Autores principales: Enato, Izehiuwa Gertrude, Sadoh, Ayebo Evawere, Ibadin, Okoeguale Michael, Odunvbun, Magdalene Erhieyouvbe, Osaigbovo, Iriagbonse Iyabo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The African Field Epidemiology Network 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789784/
https://www.ncbi.nlm.nih.gov/pubmed/36590995
http://dx.doi.org/10.11604/pamj.2022.43.80.34334

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