Cargando…

Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study

BACKGROUND: We report a retrospective case series analysis of clinical outcomes of patients with soft tissue sarcoma around the elbow. METHODS: Twenty-two patients underwent surgical tumor excision between January 1999 and May 2017, with a mean follow-up of 85.2 months. RESULTS: Six tumors were loca...

Descripción completa

Detalles Bibliográficos
Autores principales: Azurin, Edelyn S., Yamamoto, Norio, Hayashi, Katsuhiro, Takeuchi, Akihiko, Tada, Kaoru, Miwa, Shinji, Igarashi, Kentaro, Higuchi, Takashi, Yonezawa, Hirotaka, Morinaga, Sei, Asano, Yohei, Saito, Shiro, Tsuchiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789912/
https://www.ncbi.nlm.nih.gov/pubmed/36573098
http://dx.doi.org/10.1155/2022/1087726
_version_ 1784859061152382976
author Azurin, Edelyn S.
Yamamoto, Norio
Hayashi, Katsuhiro
Takeuchi, Akihiko
Tada, Kaoru
Miwa, Shinji
Igarashi, Kentaro
Higuchi, Takashi
Yonezawa, Hirotaka
Morinaga, Sei
Asano, Yohei
Saito, Shiro
Tsuchiya, Hiroyuki
author_facet Azurin, Edelyn S.
Yamamoto, Norio
Hayashi, Katsuhiro
Takeuchi, Akihiko
Tada, Kaoru
Miwa, Shinji
Igarashi, Kentaro
Higuchi, Takashi
Yonezawa, Hirotaka
Morinaga, Sei
Asano, Yohei
Saito, Shiro
Tsuchiya, Hiroyuki
author_sort Azurin, Edelyn S.
collection PubMed
description BACKGROUND: We report a retrospective case series analysis of clinical outcomes of patients with soft tissue sarcoma around the elbow. METHODS: Twenty-two patients underwent surgical tumor excision between January 1999 and May 2017, with a mean follow-up of 85.2 months. RESULTS: Six tumors were localized in the upper arm, nine in the elbow, and seven in the forearm. Sixteen tumors were deep-seated, and six were superficially located. Fifteen patients underwent wide excision, including one amputation, and 18 achieved (81.8%) negative margins histologically. Two local recurrences and four distant metastases developed. The mean Musculoskeletal Tumor Society score was 92.0% (range, 33.3–100). The 5-year local recurrence-free survival rate, metastasis-free survival rate, and overall survival rate were 90.0%, 77.0%, and 79.7%, respectively. CONCLUSIONS: Local control and limb function can have favorable outcomes when the tumor excised has a histologically negative margin without sacrificing the major structure.
format Online
Article
Text
id pubmed-9789912
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Hindawi
record_format MEDLINE/PubMed
spelling pubmed-97899122022-12-25 Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study Azurin, Edelyn S. Yamamoto, Norio Hayashi, Katsuhiro Takeuchi, Akihiko Tada, Kaoru Miwa, Shinji Igarashi, Kentaro Higuchi, Takashi Yonezawa, Hirotaka Morinaga, Sei Asano, Yohei Saito, Shiro Tsuchiya, Hiroyuki Sarcoma Research Article BACKGROUND: We report a retrospective case series analysis of clinical outcomes of patients with soft tissue sarcoma around the elbow. METHODS: Twenty-two patients underwent surgical tumor excision between January 1999 and May 2017, with a mean follow-up of 85.2 months. RESULTS: Six tumors were localized in the upper arm, nine in the elbow, and seven in the forearm. Sixteen tumors were deep-seated, and six were superficially located. Fifteen patients underwent wide excision, including one amputation, and 18 achieved (81.8%) negative margins histologically. Two local recurrences and four distant metastases developed. The mean Musculoskeletal Tumor Society score was 92.0% (range, 33.3–100). The 5-year local recurrence-free survival rate, metastasis-free survival rate, and overall survival rate were 90.0%, 77.0%, and 79.7%, respectively. CONCLUSIONS: Local control and limb function can have favorable outcomes when the tumor excised has a histologically negative margin without sacrificing the major structure. Hindawi 2022-12-17 /pmc/articles/PMC9789912/ /pubmed/36573098 http://dx.doi.org/10.1155/2022/1087726 Text en Copyright © 2022 Edelyn S. Azurin et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Azurin, Edelyn S.
Yamamoto, Norio
Hayashi, Katsuhiro
Takeuchi, Akihiko
Tada, Kaoru
Miwa, Shinji
Igarashi, Kentaro
Higuchi, Takashi
Yonezawa, Hirotaka
Morinaga, Sei
Asano, Yohei
Saito, Shiro
Tsuchiya, Hiroyuki
Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study
title Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study
title_full Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study
title_fullStr Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study
title_full_unstemmed Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study
title_short Clinical Outcomes of Soft Tissue Sarcoma around the Elbow Joint: A Retrospective Single Institution Study
title_sort clinical outcomes of soft tissue sarcoma around the elbow joint: a retrospective single institution study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789912/
https://www.ncbi.nlm.nih.gov/pubmed/36573098
http://dx.doi.org/10.1155/2022/1087726
work_keys_str_mv AT azurinedelyns clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT yamamotonorio clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT hayashikatsuhiro clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT takeuchiakihiko clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT tadakaoru clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT miwashinji clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT igarashikentaro clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT higuchitakashi clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT yonezawahirotaka clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT morinagasei clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT asanoyohei clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT saitoshiro clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy
AT tsuchiyahiroyuki clinicaloutcomesofsofttissuesarcomaaroundtheelbowjointaretrospectivesingleinstitutionstudy