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Application of CYP1A2-Template System to Understand Metabolic Processes in the Safety Assessment

Cytochrome P450 (CYP)-mediated metabolisms of four chemicals have been investigated to understand their unresolved phenomena of their metabolisms using human CYP-Template systems developed in our previous studies (Drug Metab Pharmacokinet 2019, 2021, 2022). Simulation experiments of a topoisomerase-...

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Detalles Bibliográficos
Autores principales:	Murayama, Norie, Yamada, Takashi, Yamazoe, Yasushi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Food Safety Commission, Cabinet Office, Government of Japan 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789917/ https://www.ncbi.nlm.nih.gov/pubmed/36619007 http://dx.doi.org/10.14252/foodsafetyfscj.D-22-00008

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