Regulatory T cells infiltrate the tumor-induced tertiary lymphoïd structures and are associated with poor clinical outcome in NSCLC

On one hand, regulatory T cells (Tregs) play an immunosuppressive activity in most solid tumors but not all. On the other hand, the organization of tumor-infiltrating immune cells into tertiary lymphoid structures (TLS) is associated with long-term survival in most cancers. Here, we investigated the...

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Detalles Bibliográficos
Autores principales: Devi-Marulkar, Priyanka, Fastenackels, Solène, Karapentiantz, Pierre, Goc, Jérémy, Germain, Claire, Kaplon, Hélène, Knockaert, Samantha, Olive, Daniel, Panouillot, Marylou, Validire, Pierre, Damotte, Diane, Alifano, Marco, Murris, Juliette, Katsahian, Sandrine, Lawand, Myriam, Dieu-Nosjean, Marie-Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789959/
https://www.ncbi.nlm.nih.gov/pubmed/36566320
http://dx.doi.org/10.1038/s42003-022-04356-y

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