Cargando…

Functional divergence of orthologous temperature-sensitive mutations in C. elegans and C. briggsae

To learn if orthologous mutations are temperature-sensitive in related species, we studied four C. briggsae mutations orthologous to alleles of important C. elegans genes. Both Cel-glp-4(bn2) and Cbr-glp-4(v473) are temperature-sensitive, causing sterility at 25°C. By contrast, Cel-fog-1 ( q253) is...

Descripción completa

Detalles Bibliográficos
Autores principales: Velayudhan, Satheeja Santhi, Ellis, Ronald E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790080/
https://www.ncbi.nlm.nih.gov/pubmed/36575738
http://dx.doi.org/10.17912/micropub.biology.000705