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Functional divergence of orthologous temperature-sensitive mutations in C. elegans and C. briggsae
To learn if orthologous mutations are temperature-sensitive in related species, we studied four C. briggsae mutations orthologous to alleles of important C. elegans genes. Both Cel-glp-4(bn2) and Cbr-glp-4(v473) are temperature-sensitive, causing sterility at 25°C. By contrast, Cel-fog-1 ( q253) is...
Autores principales: | Velayudhan, Satheeja Santhi, Ellis, Ronald E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Caltech Library
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790080/ https://www.ncbi.nlm.nih.gov/pubmed/36575738 http://dx.doi.org/10.17912/micropub.biology.000705 |
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