Cargando…
Advances in the pharmaceutical treatment options for canine osteoarthritis
Canine osteoarthritis is a significant cause of pain in many dogs and can therefore compromise animal welfare. As the understanding of the biology and pain mechanisms underpinning osteoarthritis grows, so do the number of treatments available to manage it. Over the last decade, there have been a num...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790257/ https://www.ncbi.nlm.nih.gov/pubmed/35285032 http://dx.doi.org/10.1111/jsap.13495 |
_version_ | 1784859134730960896 |
---|---|
author | Pye, C. Bruniges, N. Peffers, M. Comerford, E. |
author_facet | Pye, C. Bruniges, N. Peffers, M. Comerford, E. |
author_sort | Pye, C. |
collection | PubMed |
description | Canine osteoarthritis is a significant cause of pain in many dogs and can therefore compromise animal welfare. As the understanding of the biology and pain mechanisms underpinning osteoarthritis grows, so do the number of treatments available to manage it. Over the last decade, there have been a number of advances in the pharmaceutical treatment options available for dogs with osteoarthritis, as well as an increasing number of clinical trials investigating the efficacy of pre‐existing treatments. This review aims to examine the current evidence behind pharmaceutical treatment options for canine osteoarthritis, including non‐steroidal anti‐inflammatory drugs, piprants, monoclonal antibodies, adjunctive analgesics, structure modifying osteoarthritis drugs and regenerative therapies. |
format | Online Article Text |
id | pubmed-9790257 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Blackwell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-97902572022-12-28 Advances in the pharmaceutical treatment options for canine osteoarthritis Pye, C. Bruniges, N. Peffers, M. Comerford, E. J Small Anim Pract Review Canine osteoarthritis is a significant cause of pain in many dogs and can therefore compromise animal welfare. As the understanding of the biology and pain mechanisms underpinning osteoarthritis grows, so do the number of treatments available to manage it. Over the last decade, there have been a number of advances in the pharmaceutical treatment options available for dogs with osteoarthritis, as well as an increasing number of clinical trials investigating the efficacy of pre‐existing treatments. This review aims to examine the current evidence behind pharmaceutical treatment options for canine osteoarthritis, including non‐steroidal anti‐inflammatory drugs, piprants, monoclonal antibodies, adjunctive analgesics, structure modifying osteoarthritis drugs and regenerative therapies. Blackwell Publishing Ltd 2022-03-14 2022-10 /pmc/articles/PMC9790257/ /pubmed/35285032 http://dx.doi.org/10.1111/jsap.13495 Text en © 2022 The Authors. Journal of Small Animal Practice published by John Wiley & Sons Ltd on behalf of British Small Animal Veterinary Association https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Pye, C. Bruniges, N. Peffers, M. Comerford, E. Advances in the pharmaceutical treatment options for canine osteoarthritis |
title | Advances in the pharmaceutical treatment options for canine osteoarthritis |
title_full | Advances in the pharmaceutical treatment options for canine osteoarthritis |
title_fullStr | Advances in the pharmaceutical treatment options for canine osteoarthritis |
title_full_unstemmed | Advances in the pharmaceutical treatment options for canine osteoarthritis |
title_short | Advances in the pharmaceutical treatment options for canine osteoarthritis |
title_sort | advances in the pharmaceutical treatment options for canine osteoarthritis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790257/ https://www.ncbi.nlm.nih.gov/pubmed/35285032 http://dx.doi.org/10.1111/jsap.13495 |
work_keys_str_mv | AT pyec advancesinthepharmaceuticaltreatmentoptionsforcanineosteoarthritis AT brunigesn advancesinthepharmaceuticaltreatmentoptionsforcanineosteoarthritis AT peffersm advancesinthepharmaceuticaltreatmentoptionsforcanineosteoarthritis AT comerforde advancesinthepharmaceuticaltreatmentoptionsforcanineosteoarthritis |