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Airway remodelling rather than cellular infiltration characterizes both type2 cytokine biomarker‐high and ‐low severe asthma
BACKGROUND: The most recognizable phenotype of severe asthma comprises people who are blood eosinophil and FeNO‐high, driven by type 2 (T2) cytokine biology, which responds to targeted biological therapies. However, in many people with severe asthma, these T2 biomarkers are suppressed but poorly con...
Autores principales: | Khalfaoui, Latifa, Symon, Fiona A., Couillard, Simon, Hargadon, Beverley, Chaudhuri, Rekha, Bicknell, Steve, Mansur, Adel H., Shrimanker, Rahul, Hinks, Timothy S. C., Pavord, Ian D., Fowler, Stephen J., Brown, Vanessa, McGarvey, Lorcan P., Heaney, Liam G., Austin, Cary D., Howarth, Peter H., Arron, Joseph R., Choy, David F., Bradding, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790286/ https://www.ncbi.nlm.nih.gov/pubmed/35579040 http://dx.doi.org/10.1111/all.15376 |
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