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Ocular surface health of the Finnish elderly population

PURPOSE: The aim of this study was to describe the clinical ocular surface characteristics in a population‐based sample of Finnish elderly people. METHODS: This cross‐sectional study included 601 subjects (335 females, 266 males) born between the years 1933–1956 and living in Savitaipale, Finland. O...

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Autores principales: Aapola, Ulla, Nättinen, Janika, Suurkuukka, Ilona, Tuomilehto, Jaakko, Keinänen‐Kiukaanniemi, Sirkka, Saramies, Jouko, Uusitalo, Hannu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790390/
https://www.ncbi.nlm.nih.gov/pubmed/35322930
http://dx.doi.org/10.1111/aos.15130
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author Aapola, Ulla
Nättinen, Janika
Suurkuukka, Ilona
Tuomilehto, Jaakko
Keinänen‐Kiukaanniemi, Sirkka
Saramies, Jouko
Uusitalo, Hannu
author_facet Aapola, Ulla
Nättinen, Janika
Suurkuukka, Ilona
Tuomilehto, Jaakko
Keinänen‐Kiukaanniemi, Sirkka
Saramies, Jouko
Uusitalo, Hannu
author_sort Aapola, Ulla
collection PubMed
description PURPOSE: The aim of this study was to describe the clinical ocular surface characteristics in a population‐based sample of Finnish elderly people. METHODS: This cross‐sectional study included 601 subjects (335 females, 266 males) born between the years 1933–1956 and living in Savitaipale, Finland. Ocular surface health was evaluated using a comprehensive set of diagnostic tests. Previous dry eye (DE) diagnosis and history of drug treatment of DE were also recorded. Differences between sexes were estimated with Wilcoxon rank sum test and Fisher's exact test. RESULTS: Overall, 10% and 33% of people displayed signs of DE and ocular surface disease (OSD), respectively, and 30% had been previously diagnosed with DE and 36% used some form of drugs for DE. Men displayed more severe signs of meibomian gland dysfunction, blepharitis and conjunctival redness (p < 0.001), while women had higher scores in corneal staining (p = 0.005) and OSD Index (p < 0.001). CONCLUSION: Signs of OSD and DE are common among the Finnish elderly population. However, the diagnosis is affected by the diagnostic criteria used and significant differences exist between sexes. Although women were more frequently diagnosed with DE and OSD and experienced more ocular surface irritation, men had more often lid and meibomian gland‐related issues. The current diagnostic criteria of DE pose a risk of misclassifying men, who commonly display less severe symptoms in comparison with women yet exhibit more severe clinical signs associated especially with the lid margin.
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spelling pubmed-97903902022-12-28 Ocular surface health of the Finnish elderly population Aapola, Ulla Nättinen, Janika Suurkuukka, Ilona Tuomilehto, Jaakko Keinänen‐Kiukaanniemi, Sirkka Saramies, Jouko Uusitalo, Hannu Acta Ophthalmol Original Articles PURPOSE: The aim of this study was to describe the clinical ocular surface characteristics in a population‐based sample of Finnish elderly people. METHODS: This cross‐sectional study included 601 subjects (335 females, 266 males) born between the years 1933–1956 and living in Savitaipale, Finland. Ocular surface health was evaluated using a comprehensive set of diagnostic tests. Previous dry eye (DE) diagnosis and history of drug treatment of DE were also recorded. Differences between sexes were estimated with Wilcoxon rank sum test and Fisher's exact test. RESULTS: Overall, 10% and 33% of people displayed signs of DE and ocular surface disease (OSD), respectively, and 30% had been previously diagnosed with DE and 36% used some form of drugs for DE. Men displayed more severe signs of meibomian gland dysfunction, blepharitis and conjunctival redness (p < 0.001), while women had higher scores in corneal staining (p = 0.005) and OSD Index (p < 0.001). CONCLUSION: Signs of OSD and DE are common among the Finnish elderly population. However, the diagnosis is affected by the diagnostic criteria used and significant differences exist between sexes. Although women were more frequently diagnosed with DE and OSD and experienced more ocular surface irritation, men had more often lid and meibomian gland‐related issues. The current diagnostic criteria of DE pose a risk of misclassifying men, who commonly display less severe symptoms in comparison with women yet exhibit more severe clinical signs associated especially with the lid margin. John Wiley and Sons Inc. 2022-03-24 2022-12 /pmc/articles/PMC9790390/ /pubmed/35322930 http://dx.doi.org/10.1111/aos.15130 Text en © 2022 The Authors. Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Aapola, Ulla
Nättinen, Janika
Suurkuukka, Ilona
Tuomilehto, Jaakko
Keinänen‐Kiukaanniemi, Sirkka
Saramies, Jouko
Uusitalo, Hannu
Ocular surface health of the Finnish elderly population
title Ocular surface health of the Finnish elderly population
title_full Ocular surface health of the Finnish elderly population
title_fullStr Ocular surface health of the Finnish elderly population
title_full_unstemmed Ocular surface health of the Finnish elderly population
title_short Ocular surface health of the Finnish elderly population
title_sort ocular surface health of the finnish elderly population
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790390/
https://www.ncbi.nlm.nih.gov/pubmed/35322930
http://dx.doi.org/10.1111/aos.15130
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