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Selective inhibition of phosphodiesterase 4D increases tau phosphorylation at Ser214 residue

Tau is a protein that normally participates in the assembly and stability of microtubules. However, it can form intraneuronal hyperphosphorylated aggregates that are hallmarks of Alzheimer's disease and other neurodegenerative disorders known as tauopathies. Tau can be phosphorylated by multipl...

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Detalles Bibliográficos
Autores principales:	Villa, Viviana, Montalto, Giulia, Caudano, Francesca, Fedele, Ernesto, Ricciarelli, Roberta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790528/ https://www.ncbi.nlm.nih.gov/pubmed/35561079 http://dx.doi.org/10.1002/biof.1847

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