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Carboxylative efficacy of trans and cis MK7 and comparison with other vitamin K isomers

Carboxylative enzymes are involved in many pathways and their regulation plays a crucial role in many of these pathways. In particular, γ‐glutamylcarboxylase (GGCX) converts glutamate residues (Glu) into γ‐carboxyglutamate (Gla) of the vitamin K‐dependent proteins (VKDPs) activating them. VKDPs incl...

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Detalles Bibliográficos
Autores principales:	Cirilli, Ilenia, Orlando, Patrick, Silvestri, Sonia, Marcheggiani, Fabio, Dludla, Phiwayinkosi V., Kaesler, Nadine, Tiano, Luca
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2022
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790681/ https://www.ncbi.nlm.nih.gov/pubmed/35583412 http://dx.doi.org/10.1002/biof.1844

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