Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation

Regarding extracorporeal membrane oxygenation (ECMO) support against hemorrhagic conditions, there seems to be a dilemma when deciding between maintaining the circuit patency by systemic anticoagulation and increasing the risk of bleeding. We herein report two cases of diffuse alveolar hemorrhage (D...

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Autores principales: Ohta, Soichi, Matsuyoshi, Takeo, Kaneko, Hitoshi, Kosen, Daiyu, Suzuki, Hiroaki, Hamaguchi, Jun, Sato, Yuichi, Shimizu, Keiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790777/
https://www.ncbi.nlm.nih.gov/pubmed/35569985
http://dx.doi.org/10.2169/internalmedicine.9472-22
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author Ohta, Soichi
Matsuyoshi, Takeo
Kaneko, Hitoshi
Kosen, Daiyu
Suzuki, Hiroaki
Hamaguchi, Jun
Sato, Yuichi
Shimizu, Keiki
author_facet Ohta, Soichi
Matsuyoshi, Takeo
Kaneko, Hitoshi
Kosen, Daiyu
Suzuki, Hiroaki
Hamaguchi, Jun
Sato, Yuichi
Shimizu, Keiki
author_sort Ohta, Soichi
collection PubMed
description Regarding extracorporeal membrane oxygenation (ECMO) support against hemorrhagic conditions, there seems to be a dilemma when deciding between maintaining the circuit patency by systemic anticoagulation and increasing the risk of bleeding. We herein report two cases of diffuse alveolar hemorrhage (DAH) caused by myeloperoxidase (MPO) anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) successfully treated with venovenous (VV)-ECMO support, both initially started without systemic anticoagulation. Under anticoagulation-free ECMO management, we should consider the shortcomings of frequent circuit exchange and hemorrhagic diathesis related to circuit-induced disseminated intravascular coagulation (DIC).
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spelling pubmed-97907772023-01-05 Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation Ohta, Soichi Matsuyoshi, Takeo Kaneko, Hitoshi Kosen, Daiyu Suzuki, Hiroaki Hamaguchi, Jun Sato, Yuichi Shimizu, Keiki Intern Med Case Report Regarding extracorporeal membrane oxygenation (ECMO) support against hemorrhagic conditions, there seems to be a dilemma when deciding between maintaining the circuit patency by systemic anticoagulation and increasing the risk of bleeding. We herein report two cases of diffuse alveolar hemorrhage (DAH) caused by myeloperoxidase (MPO) anti-neutrophil cytoplasmic autoantibody-associated vasculitis (AAV) successfully treated with venovenous (VV)-ECMO support, both initially started without systemic anticoagulation. Under anticoagulation-free ECMO management, we should consider the shortcomings of frequent circuit exchange and hemorrhagic diathesis related to circuit-induced disseminated intravascular coagulation (DIC). The Japanese Society of Internal Medicine 2022-05-14 2022-12-01 /pmc/articles/PMC9790777/ /pubmed/35569985 http://dx.doi.org/10.2169/internalmedicine.9472-22 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Ohta, Soichi
Matsuyoshi, Takeo
Kaneko, Hitoshi
Kosen, Daiyu
Suzuki, Hiroaki
Hamaguchi, Jun
Sato, Yuichi
Shimizu, Keiki
Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation
title Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation
title_full Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation
title_fullStr Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation
title_full_unstemmed Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation
title_short Venovenous Extracorporeal Membrane Oxygenation in Diffuse Alveolar Hemorrhage Secondary to Anti-neutrophil Cytoplasmic Autoantibody-associated Vasculitis: Starting without Systemic Anticoagulation
title_sort venovenous extracorporeal membrane oxygenation in diffuse alveolar hemorrhage secondary to anti-neutrophil cytoplasmic autoantibody-associated vasculitis: starting without systemic anticoagulation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790777/
https://www.ncbi.nlm.nih.gov/pubmed/35569985
http://dx.doi.org/10.2169/internalmedicine.9472-22
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