Seronegative Full-house Nephropathy with Crohn's Disease

Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease. Lupus nephritis (LN) is a major risk factor for mortality in SLE, and glomerular “full-house” immunofluorescence staining is a well-known characteristic of LN. However, some cases of non-lupus glomerulonephritis can als...

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Autores principales: Uedono, Hideki, Tsuda, Akihiro, Ueno, Noriko, Natsuki, Yuka, Nakaya, Rino, Nishide, Kozo, Machiba, Yuri, Fujimoto, Kenta, Nakatani, Shinya, Mori, Katsuhito, Emoto, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790786/
https://www.ncbi.nlm.nih.gov/pubmed/35527024
http://dx.doi.org/10.2169/internalmedicine.8820-21
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author Uedono, Hideki
Tsuda, Akihiro
Ueno, Noriko
Natsuki, Yuka
Nakaya, Rino
Nishide, Kozo
Machiba, Yuri
Fujimoto, Kenta
Nakatani, Shinya
Mori, Katsuhito
Emoto, Masanori
author_facet Uedono, Hideki
Tsuda, Akihiro
Ueno, Noriko
Natsuki, Yuka
Nakaya, Rino
Nishide, Kozo
Machiba, Yuri
Fujimoto, Kenta
Nakatani, Shinya
Mori, Katsuhito
Emoto, Masanori
author_sort Uedono, Hideki
collection PubMed
description Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease. Lupus nephritis (LN) is a major risk factor for mortality in SLE, and glomerular “full-house” immunofluorescence staining is a well-known characteristic of LN. However, some cases of non-lupus glomerulonephritis can also present with a “full-house” immunofluorescence pattern. We recently encountered a patient with full-house nephropathy (FHN) during adalimumab administration for Crohn's disease. IgA nephropathy or idiopathic FHN was diagnosed, and treatment with steroids was started, after which there was improvement in proteinuria. The prognosis of FHN has been reported to be poor; therefore, aggressive treatment is required for such patients.
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spelling pubmed-97907862023-01-05 Seronegative Full-house Nephropathy with Crohn's Disease Uedono, Hideki Tsuda, Akihiro Ueno, Noriko Natsuki, Yuka Nakaya, Rino Nishide, Kozo Machiba, Yuri Fujimoto, Kenta Nakatani, Shinya Mori, Katsuhito Emoto, Masanori Intern Med Case Report Systemic lupus erythematosus (SLE) is a chronic autoimmune inflammatory disease. Lupus nephritis (LN) is a major risk factor for mortality in SLE, and glomerular “full-house” immunofluorescence staining is a well-known characteristic of LN. However, some cases of non-lupus glomerulonephritis can also present with a “full-house” immunofluorescence pattern. We recently encountered a patient with full-house nephropathy (FHN) during adalimumab administration for Crohn's disease. IgA nephropathy or idiopathic FHN was diagnosed, and treatment with steroids was started, after which there was improvement in proteinuria. The prognosis of FHN has been reported to be poor; therefore, aggressive treatment is required for such patients. The Japanese Society of Internal Medicine 2022-05-07 2022-12-01 /pmc/articles/PMC9790786/ /pubmed/35527024 http://dx.doi.org/10.2169/internalmedicine.8820-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Uedono, Hideki
Tsuda, Akihiro
Ueno, Noriko
Natsuki, Yuka
Nakaya, Rino
Nishide, Kozo
Machiba, Yuri
Fujimoto, Kenta
Nakatani, Shinya
Mori, Katsuhito
Emoto, Masanori
Seronegative Full-house Nephropathy with Crohn's Disease
title Seronegative Full-house Nephropathy with Crohn's Disease
title_full Seronegative Full-house Nephropathy with Crohn's Disease
title_fullStr Seronegative Full-house Nephropathy with Crohn's Disease
title_full_unstemmed Seronegative Full-house Nephropathy with Crohn's Disease
title_short Seronegative Full-house Nephropathy with Crohn's Disease
title_sort seronegative full-house nephropathy with crohn's disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790786/
https://www.ncbi.nlm.nih.gov/pubmed/35527024
http://dx.doi.org/10.2169/internalmedicine.8820-21
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