Two Distinct Cases of Adult-onset Kawasaki Disease

Kawasaki disease (KD) is a systemic vasculitis syndrome that mostly affects children under 4 years old. Among the reported KD cases, only 1% were over 10 years old. We herein report 2 cases of adult-onset KD (AKD) in 19- and 17-year-old boys diagnosed with a persistent fever and cervical lymphadenit...

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Detalles Bibliográficos
Autores principales: Onoki, Takehiko, Metoki, Takaya, Iwasawa, Shinya, Kawano, Kengo, Kimura, Masato, Kure, Shigeo, Ota, Chiharu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790799/
https://www.ncbi.nlm.nih.gov/pubmed/35466164
http://dx.doi.org/10.2169/internalmedicine.9044-21
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author Onoki, Takehiko
Metoki, Takaya
Iwasawa, Shinya
Kawano, Kengo
Kimura, Masato
Kure, Shigeo
Ota, Chiharu
author_facet Onoki, Takehiko
Metoki, Takaya
Iwasawa, Shinya
Kawano, Kengo
Kimura, Masato
Kure, Shigeo
Ota, Chiharu
author_sort Onoki, Takehiko
collection PubMed
description Kawasaki disease (KD) is a systemic vasculitis syndrome that mostly affects children under 4 years old. Among the reported KD cases, only 1% were over 10 years old. We herein report 2 cases of adult-onset KD (AKD) in 19- and 17-year-old boys diagnosed with a persistent fever and cervical lymphadenitis. Both patients showed cardiac complications, such as coronary artery dilation and myocarditis. Repeated intravenous immunoglobulin therapy was effective in the 19-year-old, while plasma exchange therapy was needed for the 17-year-old, with no sequelae noted at discharge. KD should be considered as a differential diagnosis for persistent fever in adults.
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spelling pubmed-97907992023-01-05 Two Distinct Cases of Adult-onset Kawasaki Disease Onoki, Takehiko Metoki, Takaya Iwasawa, Shinya Kawano, Kengo Kimura, Masato Kure, Shigeo Ota, Chiharu Intern Med Case Report Kawasaki disease (KD) is a systemic vasculitis syndrome that mostly affects children under 4 years old. Among the reported KD cases, only 1% were over 10 years old. We herein report 2 cases of adult-onset KD (AKD) in 19- and 17-year-old boys diagnosed with a persistent fever and cervical lymphadenitis. Both patients showed cardiac complications, such as coronary artery dilation and myocarditis. Repeated intravenous immunoglobulin therapy was effective in the 19-year-old, while plasma exchange therapy was needed for the 17-year-old, with no sequelae noted at discharge. KD should be considered as a differential diagnosis for persistent fever in adults. The Japanese Society of Internal Medicine 2022-04-23 2022-12-01 /pmc/articles/PMC9790799/ /pubmed/35466164 http://dx.doi.org/10.2169/internalmedicine.9044-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Onoki, Takehiko
Metoki, Takaya
Iwasawa, Shinya
Kawano, Kengo
Kimura, Masato
Kure, Shigeo
Ota, Chiharu
Two Distinct Cases of Adult-onset Kawasaki Disease
title Two Distinct Cases of Adult-onset Kawasaki Disease
title_full Two Distinct Cases of Adult-onset Kawasaki Disease
title_fullStr Two Distinct Cases of Adult-onset Kawasaki Disease
title_full_unstemmed Two Distinct Cases of Adult-onset Kawasaki Disease
title_short Two Distinct Cases of Adult-onset Kawasaki Disease
title_sort two distinct cases of adult-onset kawasaki disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790799/
https://www.ncbi.nlm.nih.gov/pubmed/35466164
http://dx.doi.org/10.2169/internalmedicine.9044-21
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