Diarylation of thiazolopyrimidines by laccase and their in vitro evaluation as antitumor agents

A mild and efficient method was developed for the synthesis of new derivatives of thiazolo[3,2-a] pyrimidin-3(2H)-ones from available starting materials based on the oxidation of catechols to ortho-quinone by Myceliophthora thermophila laccase (Novozym 51,003) and 1,4-addition of active methylene ca...

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Detalles Bibliográficos
Autores principales: Shahedi, Mansour, Shahani, Rojina, Habibi, Zohreh, Yousefi, Maryam, Brask, Jesper, Minaei-Tehrani, Arash, Samadi, Fatemeh Yazdi, Mohammadi, Mehdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790884/
https://www.ncbi.nlm.nih.gov/pubmed/36567332
http://dx.doi.org/10.1038/s41598-022-26820-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790884/
https://www.ncbi.nlm.nih.gov/pubmed/36567332
http://dx.doi.org/10.1038/s41598-022-26820-9

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