Cargando…
Establishment of a novel method to assess MEK1/2 inhibition in PBMCs for clinical drug development
The Raf/MEK/ERK signaling pathway plays a key role in regulating cellular proliferation, differentiation, apoptosis, cytokine production, and immune responses. However, it is also involved in diseases such as cancer, and numerous viruses rely on an active Raf/MEK/ERK pathway for propagation. This pa...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790982/ https://www.ncbi.nlm.nih.gov/pubmed/36578787 http://dx.doi.org/10.3389/fcell.2022.1063692 |