Targeting TGF-β signaling in the multiple myeloma microenvironment: Steering CARs and T cells in the right direction

Multiple myeloma (MM) remains a lethal hematologic cancer characterized by the expansion of transformed plasma cells within the permissive bone marrow (BM) milieu. The emergence of relapsed and/or refractory MM (RRMM) is provoked through clonal evolution of malignant plasma cells that harbor genomic...

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Detalles Bibliográficos
Autores principales: Rana, Priyanka S., Soler, David C., Kort, Jeries, Driscoll, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790996/
https://www.ncbi.nlm.nih.gov/pubmed/36578789
http://dx.doi.org/10.3389/fcell.2022.1059715

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790996/
https://www.ncbi.nlm.nih.gov/pubmed/36578789
http://dx.doi.org/10.3389/fcell.2022.1059715

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