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Targeting TGF-β signaling in the multiple myeloma microenvironment: Steering CARs and T cells in the right direction

Multiple myeloma (MM) remains a lethal hematologic cancer characterized by the expansion of transformed plasma cells within the permissive bone marrow (BM) milieu. The emergence of relapsed and/or refractory MM (RRMM) is provoked through clonal evolution of malignant plasma cells that harbor genomic...

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Detalles Bibliográficos
Autores principales:	Rana, Priyanka S., Soler, David C., Kort, Jeries, Driscoll, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cell and Developmental Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9790996/ https://www.ncbi.nlm.nih.gov/pubmed/36578789 http://dx.doi.org/10.3389/fcell.2022.1059715

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