High-dose steroid-responsive COVID-19-related encephalopathy with a sudden onset of dysarthria mimicking stroke: a case report

There has been limited research on encephalitis/encephalopathy, which is a less common coronavirus disease 2019 (COVID-19) neurological complication. The differentiation between stroke and encephalopathy with stroke mimickers is challenging in patients with COVID-19. Here, we describe a case of COVI...

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Autores principales: Kikutsuji, Naoya, Kataoka, Hiroshi, Kiriyama, Takao, Sugie, Kazuma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791002/
https://www.ncbi.nlm.nih.gov/pubmed/36579076
http://dx.doi.org/10.1177/11795735221147218
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author Kikutsuji, Naoya
Kataoka, Hiroshi
Kiriyama, Takao
Sugie, Kazuma
author_facet Kikutsuji, Naoya
Kataoka, Hiroshi
Kiriyama, Takao
Sugie, Kazuma
author_sort Kikutsuji, Naoya
collection PubMed
description There has been limited research on encephalitis/encephalopathy, which is a less common coronavirus disease 2019 (COVID-19) neurological complication. The differentiation between stroke and encephalopathy with stroke mimickers is challenging in patients with COVID-19. Here, we describe a case of COVID-19-related encephalopathy mimicking stroke that was successfully treated with high-dose steroid pulse therapy. The patient suddenly experienced language disturbance with a left facial droop and symmetric numbness in his upper limbs. Magnetic resonance imaging (MRI) scans revealed hyperintensities in both the white matter and splenium. No pneumonia was observed. MRI abnormalities and neurological symptoms resolved after steroid pulse therapy and administration of remdesivir. High-dose steroid pulse treatment (for 3 days) might alleviate COVID-19-related encephalopathy.
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spelling pubmed-97910022022-12-27 High-dose steroid-responsive COVID-19-related encephalopathy with a sudden onset of dysarthria mimicking stroke: a case report Kikutsuji, Naoya Kataoka, Hiroshi Kiriyama, Takao Sugie, Kazuma J Cent Nerv Syst Dis Case Report There has been limited research on encephalitis/encephalopathy, which is a less common coronavirus disease 2019 (COVID-19) neurological complication. The differentiation between stroke and encephalopathy with stroke mimickers is challenging in patients with COVID-19. Here, we describe a case of COVID-19-related encephalopathy mimicking stroke that was successfully treated with high-dose steroid pulse therapy. The patient suddenly experienced language disturbance with a left facial droop and symmetric numbness in his upper limbs. Magnetic resonance imaging (MRI) scans revealed hyperintensities in both the white matter and splenium. No pneumonia was observed. MRI abnormalities and neurological symptoms resolved after steroid pulse therapy and administration of remdesivir. High-dose steroid pulse treatment (for 3 days) might alleviate COVID-19-related encephalopathy. SAGE Publications 2022-12-22 /pmc/articles/PMC9791002/ /pubmed/36579076 http://dx.doi.org/10.1177/11795735221147218 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by-nc/4.0/This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (https://creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Kikutsuji, Naoya
Kataoka, Hiroshi
Kiriyama, Takao
Sugie, Kazuma
High-dose steroid-responsive COVID-19-related encephalopathy with a sudden onset of dysarthria mimicking stroke: a case report
title High-dose steroid-responsive COVID-19-related encephalopathy with a sudden onset of dysarthria mimicking stroke: a case report
title_full High-dose steroid-responsive COVID-19-related encephalopathy with a sudden onset of dysarthria mimicking stroke: a case report
title_fullStr High-dose steroid-responsive COVID-19-related encephalopathy with a sudden onset of dysarthria mimicking stroke: a case report
title_full_unstemmed High-dose steroid-responsive COVID-19-related encephalopathy with a sudden onset of dysarthria mimicking stroke: a case report
title_short High-dose steroid-responsive COVID-19-related encephalopathy with a sudden onset of dysarthria mimicking stroke: a case report
title_sort high-dose steroid-responsive covid-19-related encephalopathy with a sudden onset of dysarthria mimicking stroke: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791002/
https://www.ncbi.nlm.nih.gov/pubmed/36579076
http://dx.doi.org/10.1177/11795735221147218
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