Ethanol and its Nonoxidative Metabolites Promote Acute Liver Injury by Inducing ER Stress, Adipocyte Death, and Lipolysis

BACKGROUND & AIMS: Binge drinking in patients with metabolic syndrome accelerates the development of alcohol-associated liver disease. However, the underlying mechanisms remain elusive. We investigated if oxidative and nonoxidative alcohol metabolism pathways, diet-induced obesity, and adipose t...

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Detalles Bibliográficos
Autores principales: Park, Seol Hee, Seo, Wonhyo, Xu, Ming-Jiang, Mackowiak, Bryan, Lin, Yuhong, He, Yong, Fu, Yaojie, Hwang, Seonghwan, Kim, Seung-Jin, Guan, Yukun, Feng, Dechun, Yu, Liqing, Lehner, Richard, Liangpunsakul, Suthat, Gao, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791137/
https://www.ncbi.nlm.nih.gov/pubmed/36243320
http://dx.doi.org/10.1016/j.jcmgh.2022.10.002

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