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Specific DNAzymes cleave the 300–618 nt of 5′UTR to inhibit DHAV-1 translation and replication

DNAzymes effectively inhibit the expression of viral genes. Duck hepatitis A virus type-1 (DHAV-1) genomic RNA carries an internal ribosome entry site (IRES). The IRES initiates the translation of DHAV-1 via a mechanism that differs from that of cap-dependent translation. Therefore, it is an attract...

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Detalles Bibliográficos
Autores principales:	Li, Yanglin, Wei, Ling, Cheng, Anchun, Wang, Mingshu, Ou, Xumin, Mao, Sai, Tian, Bin, Yang, Qiao, Wu, Ying, Zhang, Shaqiu, Huang, Juan, Gao, Qun, Sun, Di, Zhao, Xinxin, Jia, Renyong, Liu, Mafeng, Zhu, Dekang, Chen, Shun, Yu, Yanling, Zhang, Ling, Pan, Leichang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791187/ https://www.ncbi.nlm.nih.gov/pubmed/36578574 http://dx.doi.org/10.3389/fmicb.2022.1064612

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