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An algal lectin griffithsin inhibits Hantaan virus infection in vitro and in vivo
Hantaan virus (HTNV) is the etiological pathogen of hemorrhagic fever with renal syndrome in East Asia. There are currently no effective therapeutics approved for HTNV and other hantavirus infections. We found that griffithsin (GRFT), an algae-derived lectin with broad-spectrum antiviral activity ag...
Autores principales: | Zhao, Yajing, Zhao, Ningbo, Cai, Yanxing, Zhang, Hui, Li, Jia, Liu, Jiaqi, Ye, Chuantao, Wang, Yuan, Dang, Yamei, Li, Wanying, Liu, He, Zhang, Lianqing, Li, Yuexiang, Zhang, Liang, Cheng, Linfeng, Dong, Yangchao, Xu, Zhikai, Lei, Yingfeng, Lu, Lu, Wang, Yingjuan, Ye, Wei, Zhang, Fanglin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791197/ https://www.ncbi.nlm.nih.gov/pubmed/36579342 http://dx.doi.org/10.3389/fcimb.2022.881083 |
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