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GARP dysfunction results in COPI displacement, depletion of Golgi v-SNAREs and calcium homeostasis proteins
Golgi-associated retrograde protein (GARP) is an evolutionary conserved heterotetrameric protein complex that tethers endosome-derived vesicles and is vital for Golgi glycosylation. Microscopy and proteomic approaches were employed to investigate defects in Golgi physiology in RPE1 cells depleted fo...
Autores principales: | Khakurel, Amrita, Kudlyk, Tetyana, Pokrovskaya, Irina, D’Souza, Zinia, Lupashin, Vladimir V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791199/ https://www.ncbi.nlm.nih.gov/pubmed/36578782 http://dx.doi.org/10.3389/fcell.2022.1066504 |
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