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Fc receptor engagement of HIV-1 Env-specific antibodies in mothers and infants predicts reduced vertical transmission

INTRODUCTION: Infants acquire maternal antibodies by Fc receptor transcytosis across the placenta during pregnancy. Fc receptors are expressed on immune cells and are important for activation of effector cell functions. METHODS: In this study, we evaluated Fc receptor engagement and ADCC activity of...

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Detalles Bibliográficos
Autores principales:	Barrows, Brittani M., Krebs, Shelly J., Jian, Ningbo, Zemil, Michelle, Slike, Bonnie M., Dussupt, Vincent, Tran, Ursula, Mendez-Rivera, Letzibeth, Chang, David, O’Sullivan, Anne Marie, Mann, Brendan, Sanders-Buell, Eric, Shubin, Zhanna, Creegan, Matt, Paquin-Proulx, Dominic, Ehrenberg, Philip, Laurence-Chenine, Agnes, Srithanaviboonchai, Kriengkrai, Thomas, Rasmi, Eller, Michael A., Ferrari, Guido, Robb, Merlin, Rao, Venigalla, Tovanabutra, Sodsai, Polonis, Victoria R., Wieczorek, Lindsay
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791209/ https://www.ncbi.nlm.nih.gov/pubmed/36578481 http://dx.doi.org/10.3389/fimmu.2022.1051501

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