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Chikungunya patient transcriptional signatures faithfully recapitulated in a C57BL/6J mouse model

INTRODUCTION: An adult wild-type C57BL/6J mouse model of chikungunya virus (CHIKV) infection and disease has been extensively used to study the alphaviral arthritic immunopathology and to evaluate new interventions. How well mouse models recapitulate the gene expression profiles seen in humans remai...

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Detalles Bibliográficos
Autores principales:	Bishop, Cameron R., Caten, Felipe Ten, Nakaya, Helder I., Suhrbier, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791225/ https://www.ncbi.nlm.nih.gov/pubmed/36578476 http://dx.doi.org/10.3389/fimmu.2022.1092370

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