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Intratumoral oncolytic virus V937 plus ipilimumab in patients with advanced melanoma: the phase 1b MITCI study
BACKGROUND: Intratumoral administration of V937, a bioselected, genetically unmodified coxsackievirus A21, has previously demonstrated antitumor activity in patients with advanced melanoma as monotherapy and in combination with the programmed cell death 1 (PD-1) antibody pembrolizumab. We report res...
Autores principales: | Curti, Brendan D, Richards, Jon, Hyngstrom, John R, Daniels, Gregory A, Faries, Mark, Feun, Lynn, Margolin, Kim A, Hallmeyer, Sigrun, Grose, Mark, Zhang, Yiwei, Li, Anlong, Andtbacka, Robert H I |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791411/ https://www.ncbi.nlm.nih.gov/pubmed/36564126 http://dx.doi.org/10.1136/jitc-2022-005224 |
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