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Inhibition of the different complement pathways has varying impacts on the serum bactericidal activity and opsonophagocytosis against Haemophilus influenzae type b

Defense against Haemophilus influenzae type b (Hib) is dependent on antibodies and complement, which mediate both serum bactericidal activity (SBA) and opsonophagocytosis. Here we evaluated the influence of capsule-specific antibodies and complement inhibitors targeting the central component C3, the...

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Detalles Bibliográficos
Autores principales: Muri, Lukas, Schubart, Anna, Thorburn, Christine, Zamurovic, Natasa, Holbro, Thomas, Kammüller, Michael, Pluschke, Gerd, Ispasanie, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791579/
https://www.ncbi.nlm.nih.gov/pubmed/36578495
http://dx.doi.org/10.3389/fimmu.2022.1020580

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