Morphological changes in Parkinson's disease based on magnetic resonance imaging: A mini-review of subcortical structures segmentation and shape analysis

Parkinson's disease (PD) is a neurodegenerative disorder caused by the loss of dopaminergic neurons in the substantia nigra, resulting in clinical symptoms, including bradykinesia, resting tremor, rigidity, and postural instability. The pathophysiological changes in PD are inextricably linked t...

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Autores principales: Deng, Jin-Huan, Zhang, Han-Wen, Liu, Xiao-Lei, Deng, Hua-Zhen, Lin, Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791612/
https://www.ncbi.nlm.nih.gov/pubmed/36579355
http://dx.doi.org/10.5498/wjp.v12.i12.1356
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author Deng, Jin-Huan
Zhang, Han-Wen
Liu, Xiao-Lei
Deng, Hua-Zhen
Lin, Fan
author_facet Deng, Jin-Huan
Zhang, Han-Wen
Liu, Xiao-Lei
Deng, Hua-Zhen
Lin, Fan
author_sort Deng, Jin-Huan
collection PubMed
description Parkinson's disease (PD) is a neurodegenerative disorder caused by the loss of dopaminergic neurons in the substantia nigra, resulting in clinical symptoms, including bradykinesia, resting tremor, rigidity, and postural instability. The pathophysiological changes in PD are inextricably linked to the subcortical structures. Shape analysis is a method for quantifying the volume or surface morphology of structures using magnetic resonance imaging. In this review, we discuss the recent advances in morphological analysis techniques for studying the subcortical structures in PD in vivo. This approach includes available pipelines for volume and shape analysis, focusing on the morphological features of volume and surface area.
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spelling pubmed-97916122022-12-27 Morphological changes in Parkinson's disease based on magnetic resonance imaging: A mini-review of subcortical structures segmentation and shape analysis Deng, Jin-Huan Zhang, Han-Wen Liu, Xiao-Lei Deng, Hua-Zhen Lin, Fan World J Psychiatry Minireviews Parkinson's disease (PD) is a neurodegenerative disorder caused by the loss of dopaminergic neurons in the substantia nigra, resulting in clinical symptoms, including bradykinesia, resting tremor, rigidity, and postural instability. The pathophysiological changes in PD are inextricably linked to the subcortical structures. Shape analysis is a method for quantifying the volume or surface morphology of structures using magnetic resonance imaging. In this review, we discuss the recent advances in morphological analysis techniques for studying the subcortical structures in PD in vivo. This approach includes available pipelines for volume and shape analysis, focusing on the morphological features of volume and surface area. Baishideng Publishing Group Inc 2022-12-19 /pmc/articles/PMC9791612/ /pubmed/36579355 http://dx.doi.org/10.5498/wjp.v12.i12.1356 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Minireviews
Deng, Jin-Huan
Zhang, Han-Wen
Liu, Xiao-Lei
Deng, Hua-Zhen
Lin, Fan
Morphological changes in Parkinson's disease based on magnetic resonance imaging: A mini-review of subcortical structures segmentation and shape analysis
title Morphological changes in Parkinson's disease based on magnetic resonance imaging: A mini-review of subcortical structures segmentation and shape analysis
title_full Morphological changes in Parkinson's disease based on magnetic resonance imaging: A mini-review of subcortical structures segmentation and shape analysis
title_fullStr Morphological changes in Parkinson's disease based on magnetic resonance imaging: A mini-review of subcortical structures segmentation and shape analysis
title_full_unstemmed Morphological changes in Parkinson's disease based on magnetic resonance imaging: A mini-review of subcortical structures segmentation and shape analysis
title_short Morphological changes in Parkinson's disease based on magnetic resonance imaging: A mini-review of subcortical structures segmentation and shape analysis
title_sort morphological changes in parkinson's disease based on magnetic resonance imaging: a mini-review of subcortical structures segmentation and shape analysis
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791612/
https://www.ncbi.nlm.nih.gov/pubmed/36579355
http://dx.doi.org/10.5498/wjp.v12.i12.1356
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