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Malaysian Hospital Pharmacists’ Perspectives and Their Role in Promoting Biosimilar Prescribing: A Nationwide Survey

BACKGROUND: With the increasing availability biosimilars, the role of pharmacists as drug information specialists has expanded to include promoting biosimilar acceptance among prescribers. OBJECTIVES: Our study aimed to determine Malaysian hospital pharmacists’ perspectives on biosimilars and to ide...

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Detalles Bibliográficos
Autores principales: Mohd Sani, Noraisyah, Aziz, Zoriah, Kamarulzaman, Adeeba
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791626/
https://www.ncbi.nlm.nih.gov/pubmed/36571697
http://dx.doi.org/10.1007/s40259-022-00571-5
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author Mohd Sani, Noraisyah
Aziz, Zoriah
Kamarulzaman, Adeeba
author_facet Mohd Sani, Noraisyah
Aziz, Zoriah
Kamarulzaman, Adeeba
author_sort Mohd Sani, Noraisyah
collection PubMed
description BACKGROUND: With the increasing availability biosimilars, the role of pharmacists as drug information specialists has expanded to include promoting biosimilar acceptance among prescribers. OBJECTIVES: Our study aimed to determine Malaysian hospital pharmacists’ perspectives on biosimilars and to identify factors influencing the successful promotion of biosimilars to prescribers. METHODS: This was a cross-sectional, web-based survey of hospital pharmacists across Malaysia. Multivariate logistic regression analysis was used to identify factors associated with pharmacists successfully promoting biosimilar use. RESULTS: Of the 913 responses, over 60% of pharmacists believed that patients may safely be switched from the originator product to a biosimilar and would have the same clinical outcome. Many lacked training in biosimilars (62.8%); yet most (80.6%) perceived pharmacists to play a critical role in promoting biosimilar prescribing. Multivariate logistic regression analysis showed that the strongest factor associated with pharmacists’ successful promotion of biosimilars to prescribers was having confidence (odds ratio [OR], 3.33; 95% confidence interval [CI] 2.10–5.26). Respondents who had prior experience handling biosimilars were more likely to be successful in promoting biosimilar use than those without (OR, 1.76; 95% CI 1.16–2.66). The pharmacists’ top perceived barrier to promote biosimilars in clinical practice was efficacy concerns. CONCLUSION: Although Malaysian pharmacists are in favour of biosimilars, they lack training to promote biosimilar use. Among the factors associated with successful promotion of biosimilars to prescribers are pharmacist confidence, their previous experience handling biosimilars, and prior biosimilar training. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40259-022-00571-5.
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spelling pubmed-97916262022-12-27 Malaysian Hospital Pharmacists’ Perspectives and Their Role in Promoting Biosimilar Prescribing: A Nationwide Survey Mohd Sani, Noraisyah Aziz, Zoriah Kamarulzaman, Adeeba BioDrugs Original Research Article BACKGROUND: With the increasing availability biosimilars, the role of pharmacists as drug information specialists has expanded to include promoting biosimilar acceptance among prescribers. OBJECTIVES: Our study aimed to determine Malaysian hospital pharmacists’ perspectives on biosimilars and to identify factors influencing the successful promotion of biosimilars to prescribers. METHODS: This was a cross-sectional, web-based survey of hospital pharmacists across Malaysia. Multivariate logistic regression analysis was used to identify factors associated with pharmacists successfully promoting biosimilar use. RESULTS: Of the 913 responses, over 60% of pharmacists believed that patients may safely be switched from the originator product to a biosimilar and would have the same clinical outcome. Many lacked training in biosimilars (62.8%); yet most (80.6%) perceived pharmacists to play a critical role in promoting biosimilar prescribing. Multivariate logistic regression analysis showed that the strongest factor associated with pharmacists’ successful promotion of biosimilars to prescribers was having confidence (odds ratio [OR], 3.33; 95% confidence interval [CI] 2.10–5.26). Respondents who had prior experience handling biosimilars were more likely to be successful in promoting biosimilar use than those without (OR, 1.76; 95% CI 1.16–2.66). The pharmacists’ top perceived barrier to promote biosimilars in clinical practice was efficacy concerns. CONCLUSION: Although Malaysian pharmacists are in favour of biosimilars, they lack training to promote biosimilar use. Among the factors associated with successful promotion of biosimilars to prescribers are pharmacist confidence, their previous experience handling biosimilars, and prior biosimilar training. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s40259-022-00571-5. Springer International Publishing 2022-12-26 2023 /pmc/articles/PMC9791626/ /pubmed/36571697 http://dx.doi.org/10.1007/s40259-022-00571-5 Text en © The Author(s), under exclusive licence to Springer Nature Switzerland AG 2022, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Research Article
Mohd Sani, Noraisyah
Aziz, Zoriah
Kamarulzaman, Adeeba
Malaysian Hospital Pharmacists’ Perspectives and Their Role in Promoting Biosimilar Prescribing: A Nationwide Survey
title Malaysian Hospital Pharmacists’ Perspectives and Their Role in Promoting Biosimilar Prescribing: A Nationwide Survey
title_full Malaysian Hospital Pharmacists’ Perspectives and Their Role in Promoting Biosimilar Prescribing: A Nationwide Survey
title_fullStr Malaysian Hospital Pharmacists’ Perspectives and Their Role in Promoting Biosimilar Prescribing: A Nationwide Survey
title_full_unstemmed Malaysian Hospital Pharmacists’ Perspectives and Their Role in Promoting Biosimilar Prescribing: A Nationwide Survey
title_short Malaysian Hospital Pharmacists’ Perspectives and Their Role in Promoting Biosimilar Prescribing: A Nationwide Survey
title_sort malaysian hospital pharmacists’ perspectives and their role in promoting biosimilar prescribing: a nationwide survey
topic Original Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791626/
https://www.ncbi.nlm.nih.gov/pubmed/36571697
http://dx.doi.org/10.1007/s40259-022-00571-5
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