Designing Selective Drug-like Molecular Glues for the Glucocorticoid Receptor/14-3-3 Protein–Protein Interaction

[Image: see text] The ubiquitously expressed glucocorticoid receptor (GR) is a nuclear receptor that controls a broad range of biological processes and is activated by steroidal glucocorticoids such as hydrocortisone or dexamethasone. Glucocorticoids are used to treat a wide variety of conditions, f...

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Detalles Bibliográficos
Autores principales: Pallesen, Jakob S., Munier, Claire C., Bosica, Francesco, Andrei, Sebastian A., Edman, Karl, Gunnarsson, Anders, La Sala, Giuseppina, Putra, Okky Dwichandra, Srdanović, Sonja, Wilson, Andrew J., Wissler, Lisa, Ottmann, Christian, Perry, Matthew W. D., O’Mahony, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791658/
https://www.ncbi.nlm.nih.gov/pubmed/36484727
http://dx.doi.org/10.1021/acs.jmedchem.2c01635

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