Cargando…

Sialyl-Tn Antigen-Imprinted Dual Fluorescent Core–Shell Nanoparticles for Ratiometric Sialyl-Tn Antigen Detection and Dual-Color Labeling of Cancer Cells

[Image: see text] Sialyl-Tn (STn or sialyl-Thomsen-nouveau) is a carbohydrate antigen expressed by more than 80% of human carcinomas. We here report a strategy for ratiometric STn detection and dual-color cancer cell labeling, particularly, by molecularly imprinted polymers (MIPs). Imprinting was ba...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Shan, Wang, Tianyan, Behren, Sandra, Westerlind, Ulrika, Gawlitza, Kornelia, Persson, Jenny L., Rurack, Knut
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791662/ https://www.ncbi.nlm.nih.gov/pubmed/36583127 http://dx.doi.org/10.1021/acsanm.2c03252

Ejemplares similares

Challenges in Antibody Development against Tn and Sialyl-Tn Antigens
por: Loureiro, Liliana R., et al.
Publicado: (2015)

The (Sialyl) Tn antigen: Contributions to immunosuppression in gastrointestinal cancers
por: Rajesh, Christabelle, et al.
Publicado: (2023)

The Role of Sialyl-Tn in Cancer
por: Munkley, Jennifer
Publicado: (2016)

Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens
por: Xu, Feng, et al.
Publicado: (2020)

Demethylation of the Cosmc Promoter Alleviates the Progression of Breast Cancer Through Downregulation of the Tn and Sialyl-Tn Antigens [Retraction]
Publicado: (2022)

Combined evaluation of preoperative serum sialyl-Tn antigen and carcinoembryonic antigen levels is prognostic for gastric cancer patients.
por: Takahashi, I., et al.
Publicado: (1994)

Sialyl Tn as a prognostic marker in epithelial ovarian cancer.
por: Kobayashi, H., et al.
Publicado: (1992)

Sialyl-Tn in Cancer: (How) Did We Miss the Target?
por: Julien, Sylvain, et al.
Publicado: (2012)

Humanized anti-Sialyl-Tn antibodies for the treatment of ovarian carcinoma
por: Eavarone, David A., et al.
Publicado: (2018)

Correlation between sialyl Tn antigen and lymphatic metastasis in patients with Borrmann type IV gastric carcinoma.
por: Kakeji, Y., et al.
Publicado: (1995)

Response of high-risk of recurrence/progression bladder tumours expressing sialyl-Tn and sialyl-6-T to BCG immunotherapy
por: Lima, L, et al.
Publicado: (2013)

Expression of sialyl-Tn in gastric cancer: correlation with known prognostic factors.
por: Miles, D. W., et al.
Publicado: (1995)

Siglec-15 recognition of sialoglycans on tumor cell lines can occur independently of sialyl Tn antigen expression
por: Murugesan, Gavuthami, et al.
Publicado: (2020)

Expression of sialyl-Tn sugar antigen in bladder cancer cells affects response to Bacillus Calmette Guérin (BCG) and to oxidative damage
por: Severino, Paulo F., et al.
Publicado: (2017)

Expression of sialyl-Tn predicts the effect of adjuvant chemotherapy in node-positive breast cancer.
por: Miles, D. W., et al.
Publicado: (1994)

Diagnostic value of sialyl‐Tn immunocytochemistry in breast cancer presenting with pathological nipple discharge
por: Xu, Feng, et al.
Publicado: (2021)

A combined computational-experimental approach to define the structural origin of antibody recognition of sialyl-Tn, a tumor-associated carbohydrate antigen
por: Amon, Ron, et al.
Publicado: (2018)

Sialyl-Tn vaccine induces antibody-mediated tumour protection in a relevant murine model
por: Julien, S, et al.
Publicado: (2009)

Suppression of Core 1 Gal-Transferase Is Associated with Reduction of TF and Reciprocal Increase of Tn, sialyl-Tn and Core 3 Glycans in Human Colon Cancer Cells
por: Barrow, Hannah, et al.
Publicado: (2013)

Polymeric nanoparticles targeting Sialyl-Tn in gastric cancer: A live tracking under flow conditions
por: Diniz, Francisca, et al.
Publicado: (2022)

The Breast Cancer-Associated Glycoforms of MUC1, MUC1-Tn and sialyl-Tn, Are Expressed in COSMC Wild-Type Cells and Bind the C-Type Lectin MGL
por: Beatson, Richard, et al.
Publicado: (2015)

Development of a novel target module redirecting UniCAR T cells to Sialyl Tn-expressing tumor cells
por: Loureiro, L. R., et al.
Publicado: (2018)

Novel anti-Sialyl-Tn monoclonal antibodies and antibody-drug conjugates demonstrate tumor specificity and anti-tumor activity
por: Prendergast, Jillian M., et al.
Publicado: (2017)

A cancer vaccine based on fluorine-modified sialyl-Tn induces robust immune responses in a murine model
por: Song, Chengcheng, et al.
Publicado: (2017)

Systematic review and meta-analysis of the clinical survival significance of Sialyl-Tn expression in histological tissues from cancer patients
por: Lugo, Roberto, et al.
Publicado: (2020)

Curcumin-mediated transcriptional regulation of human N-acetylgalactosamine-α2,6-sialyltransferase which synthesizes sialyl-Tn antigen in HCT116 human colon cancer cells
por: An, So-Young, et al.
Publicado: (2022)

TnT: T Antigen and Telomerase, an Explosive Route to Cancer
por: Ray, F. Andrew
Publicado: (2008)

The T/Tn-Specific Helix pomatia Lectin Induces Cell Death in Lymphoma Cells Negative for T/Tn Antigens
por: Simplicien, Mathias, et al.
Publicado: (2021)

Phenotypic Analysis of Urothelial Exfoliated Cells in Bladder Cancer via Microfluidic Immunoassays: Sialyl-Tn as a Novel Biomarker in Liquid Biopsies
por: Carvalho, Sandra, et al.
Publicado: (2020)

Thiourea‐ and Amino‐Substituted Benzoxadiazole Dyes with Large Stokes Shifts as Red‐Emitting Probe Monomers for Imprinted Polymer Layers Targeting Carboxylate‐Containing Antibiotics
por: Valderrey, Virginia, et al.
Publicado: (2022)

Fluorescent molecularly imprinted polymer particles for glyphosate detection using phase transfer agents
por: Kimani, Martha, et al.
Publicado: (2022)

Author Correction: Fluorescent molecularly imprinted polymer particles for glyphosate detection using phase transfer agents
por: Kimani, Martha, et al.
Publicado: (2023)

A randomised phase II study of sialyl-Tn and DETOX-B adjuvant with or without cyclophosphamide pretreatment for the active specific immunotherapy of breast cancer.
por: Miles, D. W., et al.
Publicado: (1996)

Novel monoclonal antibody L2A5 specifically targeting sialyl-Tn and short glycans terminated by alpha-2–6 sialic acids
por: Loureiro, Liliana R., et al.
Publicado: (2018)

Target Score—A Proteomics Data Selection Tool Applied to Esophageal Cancer Identifies GLUT1-Sialyl Tn Glycoforms as Biomarkers of Cancer Aggressiveness
por: Cotton, Sofia, et al.
Publicado: (2021)

Systematic chemoenzymatic synthesis of O-sulfated sialyl Lewis x antigens
por: Santra, Abhishek, et al.
Publicado: (2016)

Immunohistochemical analysis of Tn antigen expression in colorectal adenocarcinoma and precursor lesions
por: Dombek, Gabrielle E., et al.
Publicado: (2022)

A Novel Function of CD82/KAI1 in Sialyl Lewis Antigen-Mediated Adhesion of Cancer Cells: Evidence for an Anti-Metastasis Effect by Down-Regulation of Sialyl Lewis Antigens
por: Yoshihama, Naoya, et al.
Publicado: (2015)

Survival Advantage in Patients with Metastatic Breast Cancer Receiving Endocrine Therapy plus Sialyl Tn-KLH Vaccine: Post Hoc Analysis of a Large Randomized Trial
por: Ibrahim, Nuhad K., et al.
Publicado: (2013)

Expression of the Carbohydrate Lewis Antigen, Sialyl Lewis A, Sialyl Lewis X, Lewis X, and Lewis Y in the Placental Villi of Patients With Unexplained Miscarriages
por: Ma, Zhi, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_7onklnmanmqnk34fca8c69ks9i