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Exosomes derived from miR-338-3p-modified adipose stem cells inhibited inflammation injury of chondrocytes via targeting RUNX2 in osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a chronic degenerative disease that is one of the main causes of disability in middle-aged and elderly people. Adipose stem cell (ASC)-derived exosomes (ASC-Exo) could repair cartilage damage and treat OA. MiRNA-338-3p expression was confirmed to play a role in inh...

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Detalles Bibliográficos
Autores principales: Li, ChunLiang, Li, Wei, Pu, GengZang, Wu, JingWen, Qin, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791748/
https://www.ncbi.nlm.nih.gov/pubmed/36572886
http://dx.doi.org/10.1186/s13018-022-03437-2