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Exosomes derived from miR-338-3p-modified adipose stem cells inhibited inflammation injury of chondrocytes via targeting RUNX2 in osteoarthritis
BACKGROUND: Osteoarthritis (OA) is a chronic degenerative disease that is one of the main causes of disability in middle-aged and elderly people. Adipose stem cell (ASC)-derived exosomes (ASC-Exo) could repair cartilage damage and treat OA. MiRNA-338-3p expression was confirmed to play a role in inh...
Autores principales: | Li, ChunLiang, Li, Wei, Pu, GengZang, Wu, JingWen, Qin, Feng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791748/ https://www.ncbi.nlm.nih.gov/pubmed/36572886 http://dx.doi.org/10.1186/s13018-022-03437-2 |
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