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Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor

Regeneration of the neuromuscular junction (NMJ) leverages on extensive exchange of factors released from motor axon terminals (MATs), muscle fibers and perisynaptic Schwann cells (PSCs), among which hydrogen peroxide (H(2)O(2)) is a major pro-regenerative signal. To identify critical determinants o...

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Detalles Bibliográficos
Autores principales: Negro, Samuele, Lauria, Fabio, Stazi, Marco, Tebaldi, Toma, D’Este, Giorgia, Pirazzini, Marco, Megighian, Aram, Lessi, Francesca, Mazzanti, Chiara M., Sales, Gabriele, Romualdi, Chiara, Fillo, Silvia, Lista, Florigio, Sleigh, James N., Tosolini, Andrew P., Schiavo, Giampietro, Viero, Gabriella, Rigoni, Michela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791753/
https://www.ncbi.nlm.nih.gov/pubmed/36567321
http://dx.doi.org/10.1186/s40478-022-01495-5

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