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Hydrogen peroxide induced by nerve injury promotes axon regeneration via connective tissue growth factor
Regeneration of the neuromuscular junction (NMJ) leverages on extensive exchange of factors released from motor axon terminals (MATs), muscle fibers and perisynaptic Schwann cells (PSCs), among which hydrogen peroxide (H(2)O(2)) is a major pro-regenerative signal. To identify critical determinants o...
Autores principales: | Negro, Samuele, Lauria, Fabio, Stazi, Marco, Tebaldi, Toma, D’Este, Giorgia, Pirazzini, Marco, Megighian, Aram, Lessi, Francesca, Mazzanti, Chiara M., Sales, Gabriele, Romualdi, Chiara, Fillo, Silvia, Lista, Florigio, Sleigh, James N., Tosolini, Andrew P., Schiavo, Giampietro, Viero, Gabriella, Rigoni, Michela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791753/ https://www.ncbi.nlm.nih.gov/pubmed/36567321 http://dx.doi.org/10.1186/s40478-022-01495-5 |
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