Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases

Osteochondral lesions of the talus (OLTs) may progress to ankle arthritis needing ankle arthroplasty or arthrodesis. We report five cases of OLTs treated along the principles developed for chondrogenesis of the knee joint with autologous peripheral blood stem cells (PBSCs), resulting in repair and r...

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Autores principales: Saw, KY, Jee, CSY, Ramlan, A, Dawam, A, Saw, YC, Low, SF
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Malaysian Orthopaedic Association 2022
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791900/
https://www.ncbi.nlm.nih.gov/pubmed/36589370
http://dx.doi.org/10.5704/MOJ.2211.019
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author Saw, KY
Jee, CSY
Ramlan, A
Dawam, A
Saw, YC
Low, SF
author_facet Saw, KY
Jee, CSY
Ramlan, A
Dawam, A
Saw, YC
Low, SF
author_sort Saw, KY
collection PubMed
description Osteochondral lesions of the talus (OLTs) may progress to ankle arthritis needing ankle arthroplasty or arthrodesis. We report five cases of OLTs treated along the principles developed for chondrogenesis of the knee joint with autologous peripheral blood stem cells (PBSCs), resulting in repair and regeneration of the bone and cartilage components. Improvement in Ankle Osteoarthritis Scale (AOS) scores with minimum two years follow-up showed statistical significance (p < 0.05).
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spelling pubmed-97919002022-12-30 Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases Saw, KY Jee, CSY Ramlan, A Dawam, A Saw, YC Low, SF Malays Orthop J Case Reports Osteochondral lesions of the talus (OLTs) may progress to ankle arthritis needing ankle arthroplasty or arthrodesis. We report five cases of OLTs treated along the principles developed for chondrogenesis of the knee joint with autologous peripheral blood stem cells (PBSCs), resulting in repair and regeneration of the bone and cartilage components. Improvement in Ankle Osteoarthritis Scale (AOS) scores with minimum two years follow-up showed statistical significance (p < 0.05). Malaysian Orthopaedic Association 2022-11 /pmc/articles/PMC9791900/ /pubmed/36589370 http://dx.doi.org/10.5704/MOJ.2211.019 Text en © 2022 Malaysian Orthopaedic Association (MOA). All Rights Reserved https://creativecommons.org/licenses/by/3.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
spellingShingle Case Reports
Saw, KY
Jee, CSY
Ramlan, A
Dawam, A
Saw, YC
Low, SF
Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_full Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_fullStr Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_full_unstemmed Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_short Osteochondrogenesis with Autologous Peripheral Blood Stem Cells for Osteochondral Lesions of the Talus: Report of Five Cases
title_sort osteochondrogenesis with autologous peripheral blood stem cells for osteochondral lesions of the talus: report of five cases
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791900/
https://www.ncbi.nlm.nih.gov/pubmed/36589370
http://dx.doi.org/10.5704/MOJ.2211.019
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