Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19

Although alterations in myeloid cells have been observed in COVID-19, the specific underlying mechanisms are not completely understood. Here, we examine the function of classical CD14(+) monocytes in patients with mild and moderate COVID-19 during the acute phase of infection and in healthy individu...

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Detalles Bibliográficos
Autores principales: Maher, Allison K., Burnham, Katie L., Jones, Emma M., Tan, Michelle M. H., Saputil, Rocel C., Baillon, Laury, Selck, Claudia, Giang, Nicolas, Argüello, Rafael, Pillay, Clio, Thorley, Emma, Short, Charlotte-Eve, Quinlan, Rachael, Barclay, Wendy S., Cooper, Nichola, Taylor, Graham P., Davenport, Emma E., Dominguez-Villar, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9791976/
https://www.ncbi.nlm.nih.gov/pubmed/36572683
http://dx.doi.org/10.1038/s41467-022-35638-y

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