Cargando…

Virus-like particles containing a prefusion-stabilized F protein induce a balanced immune response and confer protection against respiratory syncytial virus infection in mice

Respiratory syncytial virus (RSV) is a serious respiratory pathogen in infants and young children worldwide. Currently, no licensed RSV vaccines are available. In this study, we explored stable prefusion conformation virus-like particles (Pre-F VLPs) as RSV vaccine candidates. RSV fusion (F) protein...

Descripción completa

Detalles Bibliográficos
Autores principales: Luo, Jin, Qin, Huan, Lei, Lei, Lou, Wange, Li, Ruitong, Pan, Zishu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792133/
https://www.ncbi.nlm.nih.gov/pubmed/36578490
http://dx.doi.org/10.3389/fimmu.2022.1054005