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In silico high-throughput screening system for AKT1 activators with therapeutic applications in sepsis acute lung injury

PURPOSE: AKT1 is an important target in sepsis acute lung injury (SALI). The current study was aim to construct a high-throughput screening (HTS) system based on the ChemDiv database (https://www.chemdiv.com/complete-list/) and use the system to screen for AKT1 activation agents, which may provide c...

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Detalles Bibliográficos
Autores principales:	Wang, Ziyi, Wang, Xuesong, Guo, Zhe, Liao, Haiyan, Chai, Yan, Wang, Ziwen, Wang, Zhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Cellular and Infection Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792167/ https://www.ncbi.nlm.nih.gov/pubmed/36579349 http://dx.doi.org/10.3389/fcimb.2022.1050497

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