DNA methylation GrimAge version 2

We previously described a DNA methylation (DNAm) based biomarker of human mortality risk DNAm GrimAge. Here we describe version 2 of GrimAge (trained on individuals aged between 40 and 92) which leverages two new DNAm based estimators of (log transformed) plasma proteins: high sensitivity C-reactive...

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Detalles Bibliográficos
Autores principales: Lu, Ake T., Binder, Alexandra M., Zhang, Joshua, Yan, Qi, Reiner, Alex P., Cox, Simon R., Corley, Janie, Harris, Sarah E., Kuo, Pei-Lun, Moore, Ann Z., Bandinelli, Stefania, Stewart, James D., Wang, Cuicui, Hamlat, Elissa J., Epel, Elissa S., Schwartz, Joel D., Whitsel, Eric A., Correa, Adolfo, Ferrucci, Luigi, Marioni, Riccardo E., Horvath, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792204/
https://www.ncbi.nlm.nih.gov/pubmed/36516495
http://dx.doi.org/10.18632/aging.204434

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