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Ganglioside GD1a enhances osteogenesis by activating ERK1/2 in mesenchymal stem cells of Lmna mutant mice

Mutations in Lmna usually cause a series of human disorders, such as premature aging syndrome (progeria) involving the skeletal system. Gangliosides are known to be involved in cell surface differentiation and proliferation of stem cells. However, the role of gangliosides in Lmna dysfunctional mesen...

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Detalles Bibliográficos
Autores principales: Kwak, Dong Hoon, Park, Ji Hye, Choi, Eul Sig, Park, Seong Hyun, Lee, Seo-Yeon, Lee, Seoul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792213/
https://www.ncbi.nlm.nih.gov/pubmed/36375476
http://dx.doi.org/10.18632/aging.204378