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Ganglioside GD1a enhances osteogenesis by activating ERK1/2 in mesenchymal stem cells of Lmna mutant mice
Mutations in Lmna usually cause a series of human disorders, such as premature aging syndrome (progeria) involving the skeletal system. Gangliosides are known to be involved in cell surface differentiation and proliferation of stem cells. However, the role of gangliosides in Lmna dysfunctional mesen...
Autores principales: | Kwak, Dong Hoon, Park, Ji Hye, Choi, Eul Sig, Park, Seong Hyun, Lee, Seo-Yeon, Lee, Seoul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792213/ https://www.ncbi.nlm.nih.gov/pubmed/36375476 http://dx.doi.org/10.18632/aging.204378 |
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