Cargando…
METTL14 Regulates Intestine Cellular Senescence through m(6)A Modification of Lamin B Receptor
N-6-Methyladenosine (m(6)A) modification is involved in multiple biological processes including aging. However, the regulation of m(6)A methyltransferase-like 14 (METTL14) in aging remains unclear. Here, we revealed that the level of m(6)A modification and the expression of METTL14 were particularly...
Autores principales: | Zhang, Zizhen, Xue, Meng, Chen, Jingyu, Wang, Zhuo, Ju, Fangyu, Ni, Jiaojiao, Sun, Jiawei, Wu, Haoyue, Zheng, Huimei, Lou, Ziwei, Zhang, Yawen, Yang, Xiaohang, Chen, Shujie, Xi, Yongmei, Wang, Liangjing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792243/ https://www.ncbi.nlm.nih.gov/pubmed/36578521 http://dx.doi.org/10.1155/2022/9096436 |
Ejemplares similares
-
Lamin A safeguards the m(6)A methylase METTL14 nuclear speckle reservoir to prevent cellular senescence
por: Zhang, Jie, et al.
Publicado: (2020) -
GDC-0326 Enhances the Effects of 5-Fu in Colorectal Cancer Cells by Inducing Necroptotic Death
por: Zhang, Zizhen, et al.
Publicado: (2021) -
Fusobacterium nucleatum reduces METTL3-mediated m(6)A modification and contributes to colorectal cancer metastasis
por: Chen,, Shujie, et al.
Publicado: (2022) -
Mettl14-driven senescence-associated secretory phenotype facilitates somatic cell reprogramming
por: Xi, Chenxiang, et al.
Publicado: (2022) -
m(6)A independent genome-wide METTL3 and METTL14 redistribution drives senescence-associated secretory phenotype
por: Liu, Pingyu, et al.
Publicado: (2021)