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Tanshinone IIA Improves Acute Gouty Arthritis in Rats through Regulating Neutrophil Activation and the NLRP3 Inflammasome

OBJECTIVES: To investigate the prevention and treatment effect of tanshinone IIA (TIIA) on acute gouty arthritis (AGA) and its mechanism. METHODS: The anti-AGA effect of TIIA was observed in vivo and in vitro. Neutrophils were isolated from the abdominal cavity of mice, and the anti-AGA effect of TI...

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Detalles Bibliográficos
Autores principales: Xu, Lianjie, Liu, Xiao, Zhang, Yurong, Jia, Tao, Li, Limei, Du, Yan, Chen, Wenhui, Zhang, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792249/
https://www.ncbi.nlm.nih.gov/pubmed/36578443
http://dx.doi.org/10.1155/2022/5851412