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Combining IP(3) affinity chromatography and bioinformatics reveals a novel protein-IP(3) binding site on Plasmodium falciparum MDR1 transporter

Intracellular Ca(2+) mobilization induced by second messenger IP(3) controls many cellular events in most of the eukaryotic groups. Despite the increasing evidence of IP(3)-induced Ca(2+) in apicomplexan parasites like Plasmodium, responsible for malaria infection, no protein with potential function...

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Detalles Bibliográficos
Autores principales: Alves, Eduardo, Nakaya, Helder, Guimarães, Euzébio, Garcia, Célia R.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792294/
https://www.ncbi.nlm.nih.gov/pubmed/36582189
http://dx.doi.org/10.1016/j.crmicr.2022.100179