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GTS-21, a selective alpha7 nicotinic acetylcholine receptor agonist, ameliorates diabetic nephropathy in Lepr(db/db) mice

Diabetic nephropathy (DN) is a serious complicating factor in human type 2 diabetes mellitus (T2DM), and it commonly results in end-stage renal disease (ESRD) that requires kidney dialysis. Here, we report that the α7 nicotinic acetylcholine receptor (α7nAChR) agonist GTS-21 exerts a novel anti-infl...

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Detalles Bibliográficos
Autores principales:	Meng, Qinghe, Tian, Xinghan, Li, Junwei, Pruekprasert, Napat, Dhawan, Ravi, Holz, George G., Cooney, Robert N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9792461/ https://www.ncbi.nlm.nih.gov/pubmed/36572735 http://dx.doi.org/10.1038/s41598-022-27015-y

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